Researcher uses microscale technology to isolate rare cells
In a blood sample taken from a cancer patient, there may be a single circulating tumor cell among hundreds of thousands of other cells. These tumor cells can provide valuable information about how...
View ArticleScientists unveil the structure of myelin
New research has shed light on the way in which our nerves conduct electrical signals around our bodies. The structure of myelin, the layer of insulating fat surrounding nerve cells of vertebrates, has...
View ArticleResearchers develop pioneering new method to map enzyme activity
Researchers from Cardiff University have pioneered a new technique that will enable scientists to precisely pinpoint the areas on an enzyme that help to speed up chemical reactions.
View ArticleFaster, not stronger: How a protein regulates gene expression
Inside the cell, DNA is tightly coiled and packed with several proteins into a structure called "chromatin", which allows DNA to fit in the cell while also preventing genes from being expressed at the...
View ArticleDisabling antibiotic-resistant bacteria
Dreaded bacterial-related diseases have killed untold numbers of humans over the centuries. Today, two million illnesses and nearly 23,000 deaths can be attributed to antibiotic-resistant bacteria...
View ArticleStudy points to unexplored realm of protein biology, drug targets
Scientists at The Scripps Research Institute (TSRI) have devised a powerful set of chemical methods for exploring the biology of proteins.
View ArticleStudy leads to 3-D structures of key molecule implicated in diseases of the...
Scientists at The Scripps Research Institute (TSRI) have teamed up with several other institutions and pharmaceutical companies, including the University of Southern California (USC), San Diego's...
View ArticleResearchers bring to life proteins' motion
Advancing the field of structural biology that underpins how things work in a cell, researchers have identified how proteins change their shape when performing specific functions. The study's fresh...
View ArticleScientists find evidence of key ingredient during dawn of life
Before there were cells on Earth, simple, tiny catalysts most likely evolved the ability to speed up and synchronize the chemical reactions necessary for life to rise from the primordial soup. But what...
View ArticleExpanding the DNA alphabet: 'Extra' DNA base found to be stable in mammals
Researchers from the University of Cambridge and the Babraham Institute have found that a naturally occurring modified DNA base appears to be stably incorporated in the DNA of many mammalian tissues,...
View ArticleResearchers create synthetic membranes that grow like living cells
Chemists and biologists at UC San Diego have succeeded in designing and synthesizing an artificial cell membrane capable of sustaining continual growth, just like a living cell.
View ArticleX-raying ion channels
The Nobel Prize winner Roderick MacKinnon suggested that ion channels were like rigid tubes through which molecules of varying size move. Now it seems that he was wrong: a team of scientists from SISSA...
View ArticleResearchers develop a new family of bioinspired antibiotic compounds
A group of researchers, led by Francesc Rabanal, professor in the Department of Organic Chemistry of the University of Barcelona (UB), has published the first results of a study of a new antibacterial...
View ArticleRapid chemical synthesis of proteins by a new amino acid partner
The development of new methods for the chemical synthesis of proteins is highly significant to access a range of proteins inaccessible by conventional approaches. Dr. Ivano Pusterla and Prof. Jeffery...
View ArticleSynthetic biology used to engineer new route to biochemicals
Living cells can make a vast range of products for us, but they don't always do it in the most straightforward or efficient way. Shota Atsumi, a chemistry professor at UC Davis, aims to address that...
View ArticleA person's diet, acidity of urine may affect susceptibility to UTIs
The acidity of urine—as well as the presence of small molecules related to diet—may influence how well bacteria can grow in the urinary tract, a new study shows. The research, at Washington University...
View ArticleA gel that can make drugs last longer
Researchers at the Institute of Bioengineering and Nanotechnology (IBN) of A*STAR have developed a drug-delivering hydrogel to treat chronic diseases such as hepatitis C, a liver disease that kills...
View ArticleUsing bacterial 'fight clubs' to find new drugs
Creating bacterial "fight clubs" is an effective way to find new drugs from natural sources.
View ArticleOU professor developing vaccine to protect global communities from malaria
A University of Oklahoma professor studying malaria mosquito interaction has discovered a new mosquito protein for the development of a new vaccine that is expected to stop the spread of the disease in...
View ArticleA single molecule in the building blocks of life
The world is built up of molecules that join together and form different building blocks. New software makes it easier to zoom right in to the individual molecule.
View ArticleScientists unravel elusive structure of HIV protein
HIV, or human immunodeficiency virus, is the retrovirus that leads to acquired immunodeficiency syndrome or AIDS. Globally, about 35 million people are living with HIV, which constantly adapts and...
View ArticleWhat makes fireflies glow?
As fireflies are delighting children across the country with their nighttime displays, scientists are closing in on a better understanding of how the insects produce their enchanting glow. They report...
View ArticleMarine biologists clarify how specialized cells in squid skin are able to...
Perhaps not the brightest of cephalopods, the California market squid (Doryteuthis opalescens) has amazing light-manipulating abilities. While this species shares the gift of camouflage with most other...
View ArticleScientists advance cancer drug design with image of key protein
Scientists have pioneered the use of a high-powered imaging technique to picture in exquisite detail one of the central proteins of life – a cellular recycling unit with a role in many diseases.
View ArticleThe bioprinted 'play dough' capable of cell and protein transfer
Scientists have developed a new technique allowing the bioprinting at ambient temperatures of a strong paste similar to 'play dough' capable of incorporating protein-releasing microspheres.
View Article'Invisible' protein structure explains the power of enzymes
A research group at Umeå University in Sweden has managed to capture and describe a protein structure that, until now, has been impossible to study. The discovery lays the base for developing designed...
View ArticleHow cancer cells avoid shutdown
A mechanism beyond the level of gene regulation, which is often the underlying reason for changes in protein levels, does enable the strong accumulation of a tumour promoting protease in stressed...
View ArticleProtein suggests a new strategy to thwart infection
The newfound ability of a protein of the intestines and lungs to distinguish between human cells and the cells of bacterial invaders could underpin new strategies to fight infections.
View ArticleIon channel mechanics yield insights into optogenetics experiments
Optogenetics techniques, which allow scientists to map and control nerve cells using light stimulation, are being used to study neural circuits in the brain with unprecedented precision. This...
View ArticleKiller sea snail a target for new drugs
University of Queensland pain treatment researchers have discovered thousands of new peptide toxins hidden deep within the venom of just one type of Queensland cone snail.
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